Pyrroloquinoline quinone preserves mitochondrial function and prevents oxidative injury in adult rat cardiac myocytes
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چکیده
منابع مشابه
Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo.
BACKGROUND The serine-threonine kinase Akt is activated by several ligand-receptor systems previously shown to be cardioprotective. Akt activation reduces cardiomyocyte apoptosis in models of transient ischemia. Its role in cardiac dysfunction or infarction, however, remains unclear. METHODS AND RESULTS We examined the effects of a constitutively active Akt mutant (myr-Akt) in a rat model of ...
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ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 2007
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2007.08.041